Fisher Scientific PI48910 - Chemistry Reag… | USA MedPremium
Chemistry Reagent Thermo Scientific™ MSTFA (N-Methyl-N-Trimethylsilyltrifluoroacetamide) 98 to 100% 10 X 1 mL
USAMP#98848259SKU: PI48910Thermo Scientific™
Product Spotlight
Trimethylsilyl donor strength comparable to BSA and BSTFA
Reacts to replace labile hydrogen's on a wide range of polar compounds with a Si(CH3)3 group
Used to prepare volatile and thermally stable derivatives for GC and MS
Volatile byproduct, N-methyltrifluoroacetamide, has an even lower retention time than MSTFA
Often TMS derivatives of small molecules can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent front
Addition of Thermo Scientific TMCS aids derivatization of amides, secondary amines and hindered hydroxyls not derivatized by MSTFA alone